Real Madrid took full advantage of Barcelona's shock defeat at Real Valladolid with a 3-0 home win over 10-man Levante on Sunday that put Carlo Ancelotti's in-form side three points clear at the top of La Liga.
Robert Lewandowski scored a brilliant free kick to give Bayern Munich a 1-0 win over Atletico Madrid in their last Champions League Group D outing on Tuesday, ending the 100 percent record of their opponents. The Poland international curled the ball over the wall and into the corner of the net in the 28th minute but the goal had no impact on the final standings with Atletico guaranteed top spot and Bayern in second place.
Lionel Messi scored his 55th international goal to become his country's all-time leading scorer as Argentina thrashed hosts the United States 4-0 to ease into the final of the Centenary Copa America on Tuesday.
News of all that's transpired on and off the football field.
Barcelona made a disappointing start to their Champions League campaign by losing 2-1 to AS Monaco on Thursday.
Bayern Munich won the Champions League for a sixth time by beating Paris St Germain 1-0 in Sunday's final
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions Juventus' long unbeaten streak in Italy came to an end.
Cristiano Ronaldo scored a perfect hat-trick inside 32 minutes as Juventus bounced back from their midweek Champions League exit by beating Cagliari 3-1 away in Serie A on Sunday.
Barcelona winger Raphinha secured a 1-0 win in LaLiga for the second straight week this time at Athletic Bilbao as his side tightened their grip on top spot.
The table suggests Louis van Gaal is making progress at Manchester United but winning matches has never been good enough on its own at the Theatre of Dreams.
Real Madrid keeper Iker Casillas believes the European champions have a side with the potential to be one of the all-time greats and it will be with likely trepidation that an off-colour Liverpool visit the Bernabeu on Tuesday.
Manchester United's early season problems were compounded by a humiliating 4-0 loss to third-tier Milton Keynes Dons in the League Cup second round on Tuesday leaving new manager Louis van Gaal still looking for his first win.
Real Madrid tore apart Bayern Munich's ragged defence with a ruthless first-half display as they thrashed the defending champions 4-0 in their own stadium to reach their first Champions League final for 12 years.
Images from the football matches played across Europe on Tuesday.
Barcelona snapped a four-match winless run in La Liga with a 4-2 home victory over title rivals Sevilla on Saturday to reclaim top spot but the triumph was marred by talisman Lionel Messi fracturing his arm and being ruled out for three weeks.
A summary of Thursday's South American World Cup qualifiers.
Photos from the 2018 World Cup qualifiers played on Tuesday
Roger Martinez scored an outstanding goal as Colombia beat Argentina 2-0 in an exciting finale to a Copa America Group B opener on Saturday that burst into life after a sluggish start.
The goal gave Argentina all three points and condemned their neighbors to a losing start to their Copa campaign.
Manchester United took over at the top of the Premier League while Barcelona's Argentine forward Lionel Messi could be out for up to two months with a knee injury and rampant Bayern Munich extended their perfect start to seven league wins.
"I want to reach the highest level possible as a player and I think the most important thing is that at the end of the season we can be happy and maybe have some titles," playmaker De Bruyne told the City website (www.mcfc.co.uk).
Real Madrid's early-season woes deepened when they lost 2-1 at home to La Liga champions Atletico Madrid, while substitute Neymar struck twice in Barcelona's 2-0 win against visiting Athletic Bilbao on Saturday.
News of all that's transpired on and off the football field
Substitute Dusan Tadic fired the only goal as Southampton recorded a first league win over Manchester United for 27 years on Sunday, climbing above them into third in the Premier League.
Manchester United consolidated their fourth place, on 22 points, after first-half goals from Chris Smalling and Wayne Rooney and a brilliant, morale-boosting strike from Robin van Persie after the break sealed a 3-0 victory over Hull City.
Written off last season as a sub-standard misfit with a comical haircut, there are signs that Marouane Fellaini is finally beginning to feel comfortable in a red Manchester United shirt.
After an indifferent Premier League start and without an away win this season, Manchester United manager Louis van Gaal's belief that his side can still win the Premier League is misplaced, says former club captain Gary Neville.
Karim Benzema scored his sixth goal in four games as Real Madrid beat Alaves 3-0 on Sunday for a fourth successive La Liga victory which took the European champions to within eight points of leaders Barcelona.
Barcelona coach Ronald Koeman has defended centre-back Gerard Pique's right to make comments about referees favouring Real Madrid.
A round-up Wednesday's football news on and off the field.
News of all that's transpired on and off the football field
Monaco's firepower was far too hot to handle for Olympique de Marseille as the Principality side moved top of the French Ligue 1 standings with a 4-0 home win on Saturday.
Atletico Madrid took advantage of Barcelona's slip-up to go top of La Liga with a 4-0 victory over Real Sociedad as Real Madrid drew 1-1 at Athletic Bilbao and Cristiano Ronaldo was sent off on Sunday.
A summary of Saturday's action in Ligue 1, La Liga and Serie A.
News of all that's transpired on and off the football field
Photos from the Champions League matches played on Wednesday.
Europa League kings Sevilla breezed past Manchester United into the semi-finals of their favourite competition as Youssef En Nesyri scored twice
Lionel Messi came off the bench to preserve Barcelona's unbeaten run in La Liga with a sensational late equaliser in a thrilling 2-2 draw at Sevilla on Saturday as the runaway leaders came back from two goals down in the space of a minute.
Barcelona forwards Ousmane Dembele and Lionel Messi fired the Catalans to a confidence-boosting 2-0 win at in-form Sevilla on Saturday to keep the pressure on La Liga leaders Atletico Madrid.
Sweden striker Zlatan Ibrahimovic crowned a triumphant homecoming with a second-half goal as Paris St Germain crushed Malmo 5-0 on Wednesday to book a place in the last 16 of the Champions League.